Skin Supplements / Skin Boosters / Subcutaneous IV Drip[Salmon-derived PN] Endran Hiller
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[Salmon-derived PN] Endran Hiller
Endran Hiller is a treatment that injects polynucleotide (PN) derived from salmon into the skin. This helps alleviate dryness within the skin and improve the overall skin environment, promoting increased elasticity and maintaining healthy skin. *VAT separate
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Distinction of PN Booster Treatment
1. Same Ingredient Composition, Affordable Cost
It is the same as the core ingredient of the widely known salmon injection.
The core ingredient, PN, is included in the same concentration, offering similar expected effects while reducing cost burden.
2. Not a Simple Injection, but a Precisely Planned Procedure
By injecting PN into the precise layer and depth, considering skin structure, the treatment's effectiveness is enhanced.
3. Accuracy Verification Through Observation of Embossment
Immediately after the treatment, we observe the embossment on the skin together with the patient to confirm that the PN ingredient has been accurately injected into the target area.
4. Consultation and Treatment Directly Conducted by the Director
After thoroughly diagnosing the patient's skin condition and past treatment history, we establish and proceed with a personalized treatment plan.
5. Minimizing Skin Irritation and Concluding with Recovery in Mind
Using a Jaun-go modeling pack helps soothe sensitive skin comfortably and reduces recovery burden.
6. Adjusting Embo Spacing for Each Treatment Area
For areas like the cheeks or forehead, the spacing is adjusted for optimal effect, while sensitive areas like around the eyes or mouth are treated more finely. This is determined by thoroughly assessing skin thickness, elasticity, and wrinkle direction. Even with the same treatment volume, the procedure is customized for each area.
PN Booster Treatment, Why Consider It?
1. Same Ingredients, an Alternative for a Wise Choice
The patent period for PN (Polynucleotide), the main ingredient of the widely known salmon injection, has expired. Now, various products based on the same salmon-derived PN are being released.
Our clinic's PN Booster also contains the same ingredients,
helping you receive treatment at a relatively affordable cost.
We propose a realistic PN treatment that maintains the expected effects while lowering the price burden.
If you are considering a cost-effective PN injection, our clinic's PN Booster can be an option.
2. Injection Method More Important Than the Ingredient Itself
It is difficult to expect the same results just because a product contains PN.
Our clinic's PN Booster treatment does not simply mean an injection process.
We carefully calculate and inject into the correct skin layer, appropriate depth, and necessary dosage.
Considering each patient's skin thickness, degree of damage, and pore structure, we adjust the depth to suit each skin layer for the treatment.
Only through this method of treatment can true dermal remodeling and collagen regeneration be expected.
3. Confirming Injection Location with Embo Phenomenon
At our clinic, we verify whether the PN ingredient has been accurately injected into the skin
through a visual confirmation process by both the medical staff and the patient.
The embossment phenomenon is not merely a side effect, but can be an indicator that the medication has appropriately reached the target area.
Therefore, after the treatment, we have a procedure to confirm the embossment with the patient.
We approach this with the perspective that a brief observation of the embossment can positively influence satisfaction with the treatment results.
4. 1:1 Customized Consultation and Treatment Directly Conducted by the Director
Rather than the typical explanation method handled by a consultation manager, the director emphasizes direct communication with the patient.
The director personally and thoroughly assesses and confirms the patient's skin condition, sensitivity, past treatment history, as well as currently used cosmetics or medications,
throughout the entire treatment process.
This process helps the PN ingredient to work more effectively.
At the same time, we strive to reduce unnecessary inflammation or the risk of side effects.
5. Minimizing Irritation and Aiming for Rapid Recovery
After PN treatment, we include the application of Jaungo modeling mask as a basic step.
We provide traditional Korean medicine complex soothing care that quickly calms down heat sensation, redness, and sensitivity that may appear after the treatment.
This can help soothe the skin in advance before excessive immune reactions occur.
Through this process, even those with thin or sensitive skin can comfortably receive PN treatment.
We strive to provide integrated care that considers not only the treatment process but also skin recovery.
6. Customized Embossing Interval Design by Area
When performing PN Booster treatment, we meticulously plan not only the injection areas but also the injection intervals.
For example, in areas like the cheeks or forehead, where the dermis layer is relatively thick and wide,
the PN component can diffuse widely from a single point, allowing for good results even with intervals of approximately 1-1.5cm.
Conversely, in areas where the skin is thin and has many fine wrinkles, such as around the eyes or mouth,
we inject more delicately at 0.5cm intervals to help improve skin texture.
If the skin is generally thin or has many sunken areas,
or if the skin texture structure has become irregular due to laser treatments, we consider injecting more densely even in areas like the cheeks or forehead.
By comprehensively considering skin thickness, elasticity, wrinkle direction, and treatment goals,
we customize the treatment plan, including the position and interval of the embossing, for each individual.
Even when using the same dose of PN, different treatment methods can lead to different results.
A key feature of PN Booster treatment is that it provides personalized, non-mechanical treatment tailored to each individual's skin condition.
What effects can you expect from PN Booster treatment?
1. Induces collagen and elastin production, leading to thicker, more elastic skin.
PN (polynucleotide), derived from salmon, stimulates fibroblasts in the skin's dermal layer,
and promotes the production of collagen and elastin.
→ This leads to increased skin thickness, helps reduce fine wrinkles and restore elasticity,
and can also be expected to improve pores.
2. Contributes to the recovery of damaged skin barriers and strengthens self-regeneration.
PN promotes the secretion of growth factors such as TGF and FGF, aiding epidermal cell regeneration and contributing to skin barrier recovery.
→ This can positively impact the improvement of internal dryness, reduction of sensitivity, and enhancement of the skin's natural healing power.
It can especially help accelerate the recovery process of sensitized skin after laser or peeling treatments.
3. Naturally improving skin changes
PN Booster is not a treatment that adds volume to the skin like fillers or paralyzes specific muscles like Botox.
→ Instead, it enhances the skin's natural regenerative power, helping to smooth skin texture, alleviate internal dryness, and improve makeup adhesion.
If you are seeking more natural skin improvement and health, you may consider PN Booster treatment.
Mechanism of Action of PN Booster
1. Inducing skin structure improvement through fibroblast activation
The PN (polynucleotide) component used in PN Booster,
consists of high-purity DNA fragments extracted from salmon. When this component is injected into the skin,
it acts similarly to skin damage signals, inducing the activation of fibroblasts.
Activated fibroblasts produce skin components such as collagen, elastin, and hyaluronic acid,
contributing to improved skin thickness and elasticity, and creating a healthy skin structure.
2. Restoring skin's self-regenerative power through growth factor secretion promotion
Activated fibroblasts play a role in secreting various growth factors related to skin regeneration.
TGF-β factors help collagen synthesis.
FGF plays a role in promoting skin regeneration and recovery.
VEGF contributes to improving microcirculation in the skin.
These growth factors create an environment where the skin can regenerate itself.
As a result, they help the epidermis and skin barrier recover naturally.
Through this process, skin sensitivity can be reduced, inner dryness alleviated, and overall restorative power enhanced.
3. Improved dermal density can give the skin a fuller sensation.
Kkeut Hanuiwon PN Booster primarily acts on the dermis, a crucial part of the skin.
PN ingredients help reform the ECM (extracellular matrix), a major component of the dermis.
It encourages the dermal tissue to be more densely filled with collagen, hyaluronic acid, and various proteins.
This can improve skin elasticity and volume. Skin texture can also be refined, leading to makeup blending more smoothly.
4. It helps reduce skin irritation, promotes rapid recovery, and assists with anti-inflammatory action.
PN ingredients aid in skin regeneration while also regulating subtle inflammatory responses within the skin.
Chronic redness
Skin sensitive to external stimuli
Sensitive reactions occurring after laser procedures
Even in such cases, it can help alleviate inflammatory reactions in the skin and promote a healthy recovery process.
Thanks to these characteristics, Kkeut Hanuiwon PN Booster is known as a PN treatment that can be considered for relatively sensitive skin.
Kkeut Hanuiwon PN Booster Treatment Procedure
1. Skin Condition Analysis and Diagnosis
By thoroughly assessing the patient's skin thickness, elasticity, and sensitivity,
we carefully determine the depth and method of PN injection.
2. Individual Consultation with the Director
The areas requiring skin improvement and the treatment zones
are directly examined by the director, who then devises a treatment plan.
A customized treatment plan is established, considering each individual's skin characteristics.
3. Anesthetic Cream Application
As this treatment involves direct delivery of PN ingredients into the dermis,
sufficient numbing time of about 20 to 30 minutes is provided
to minimize any discomfort that may occur during the procedure.
4. Kkeut Hanuiwon PN Booster Main Procedure
PN ingredients are precisely injected at the pre-planned depth and target locations.
The position of the injected PN is immediately confirmed via a visible elevation, and
if necessary, immediate fine adjustments are made to enhance the accuracy of the procedure.
5. Soothing Treatment with Jaungo Modeling Pack
Immediately after the procedure, a Jaungo Modeling Pack is used to
quickly soothe needle marks, erythema (redness), and heat sensation.
This helps prevent excessive immune responses and ensures a comfortable conclusion to the skin recovery process.
Kkeut Hanuiwon PN Booster Recommended Treatment Cycle and Maintenance Period
1. Intensive Initial Treatment (usually 3 sessions)
For the full effect of PN ingredients, typically 3 treatment sessions, spaced about 1 month apart, can be considered.
This is because PN ingredients require time to fully reach and accumulate in the skin's dermis layer.
During this process, fibroblasts within the skin can be activated.
This helps collagen remodeling progress consistently.
As a result, it contributes to the stable progress of the skin regeneration process.
2. Maintenance Treatment
To experience the improved effects for a longer period,
a maintenance treatment can be considered approximately once every 6 months to 1 year.
The duration of treatment effects may vary depending on an individual's skin condition and lifestyle.
Generally, after the recommended 3 treatment sessions, the effects can last for approximately 6 to 12 months.
3. How long do the effects last?
Once the collagen remodeling process is complete,
improvements in skin texture, elasticity, and density can be expected to last for an average of 6 months or more.
However, in some situations, the duration of maintenance may be shorter.
If the skin is naturally very thin or highly damaged,
the duration may differ if there are lifestyle habits that negatively impact skin health, such as smoking or excessive UV exposure.
4. When can I expect to feel the effects after treatment?
Immediately after the procedure, temporary embossing or mild swelling may occur.
After approximately 1 week, you may notice that makeup applies better and your skin texture begins to refine.
By weeks 2 to 3, you can expect improved skin elasticity, increased density, and a softening of fine lines.
After completing all 3 treatment sessions, you will likely notice more significant changes in your skin's internal structure and an overall improvement in your skin condition.
How much pain is involved with PN Booster treatments?
The pain experienced during the procedure can be described as a tolerable tingling sensation.
Since PN ingredients are injected into the skin's dermis, it is not completely painless.
However, sufficient numbing is performed before the treatment, so most patients find the procedure comfortable.
Differences in Pain by Area
Around the cheeks, forehead, and mouth, little to no pain may be felt.
In areas like around the eyes, bridge of the nose, and chin, a momentary stinging sensation may occur.
In areas with larger pores, a heavy, pressing sensation might be felt.
Methods to Reduce Pain During Treatment
Allow sufficient time for the numbing cream to take full effect.
During the procedure, inject the ingredients slowly and in small amounts to minimize irritation.
Monitor the patient's pain level in real-time during the treatment.
After the treatment, we soothe the skin with a calming pack for a comfortable finish.
Cases where PN Booster might be considered
1. Individuals with noticeably increased fine lines
This can be especially helpful for those who have many fine lines around the eyes, on the cheeks, and around the mouth.
It may be suitable for individuals who find lifting or filler treatments burdensome but desire natural wrinkle improvement.
2. Individuals whose skin has become sensitive and frequently red
It may also be considered by those with sensitive skin that easily reacts to changes in cosmetics or who frequently experience facial redness.
Those who want to restore a weakened skin barrier to health
Also suitable for those whose makeup often cakes due to inner dryness.
This is when you are concerned about skin that feels oily on the surface but dry and tight underneath, and makeup that lifts off.
Suitable for dehydrated skin that continues to feel tight inside despite sufficient moisturizing.
Suitable for those whose skin has become sensitive and fatigued due to frequent treatments.
Used to aid recovery when skin has thinned or become sensitive due to laser, peeling, or other treatments.
Recommended when you want to improve overall skin condition and boost its fundamental strength.
Can be considered when you want to improve skin density and surface texture.
Helpful when skin elasticity has decreased, giving an overall loose and spread-out appearance.
May be suitable for those with decreased elasticity in the cheekbone or cheek areas, and uneven, unrefined skin texture.
Embossing Reaction After PN Booster Treatment
PN Booster After treatment, small, convex shapes resembling embossing may temporarily appear on the skin.
This embossing can be interpreted as a positive sign that the medication has been effectively delivered to the skin's dermal layer.
The phenomenon of the skin appearing slightly raised is a natural reaction, and you can have positive expectations regarding the treatment's effects.
Typically, the embossing naturally disappears within 1-2 days.
For those with thin or dry skin, it may last about 2-3 days, and in sensitive areas like around the eyes or mouth, it can persist for up to 4 days.
Rarely, the embossing may persist for 5-7 days or longer, but
if it is not accompanied by unusual pain, heat, or excessive redness, there is no need to worry greatly.
This can also be seen as a positive outcome, where the medication is slowly absorbed, acting on the skin for a longer period.
Post-Treatment Precautions
✔ Slight protrusions, redness, and mild discomfort in the treated area may appear for about 2-3 days.
✔ Small bruises, needle marks, and slight swelling may persist for about 1-2 weeks after the treatment.
✔ To minimize irritation to the treated area, it is recommended to avoid alcohol, smoking, saunas, swimming pools, and strenuous exercise for at least 7 days.
✔ After treatment, pay special attention to skin calming and moisturizing care, and always apply sunscreen thoroughly when going out.
Q&A
고객님들이 가장 많이 물어보시는 내용을 모았습니다.
Is it similar to Rejuran treatment?
Endran Hiller contains the same polynucleotide (PN) component as Rejuran. It can particularly help alleviate dryness within the skin and positively contribute to creating a healthy skin environment.
What is the appropriate treatment interval?
Generally, we recommend undergoing a total of 3 treatments with a one-month interval between each.


