[Brightening Intensive Care] Glutathione Jade White Skin Management

Brightening Management using Glutathione

What is Glutathione?

Glutathione is an important antioxidant abundantly present in various organs of our body, including the liver, kidneys, and brain.

This compound helps alleviate cell damage by eliminating reactive oxygen species (ROS). It also assists the actions of other antioxidants like vitamins C and E, thereby playing an important role in protecting cells.

The Effect of Glutathione on Skin Tone

Beyond its simple antioxidant function, glutathione can also help make your skin tone clearer and more even.

Inhibition of Melanin-Producing Enzymes

It inhibits the activity of tyrosinase, an enzyme responsible for producing skin pigment, thereby preventing excessive pigment formation.

Induction of Changes in Melanin Type

Glutathione can contribute to overall skin brightening by inducing the production of relatively lighter-colored pheomelanin instead of dark and dense eumelanin.

Alleviation of Pigmentation Through Antioxidant Action

Reactive oxygen species generated by factors such as UV radiation, heat, and inflammatory responses can promote melanin production. By eliminating these active oxygen species, glutathione helps inhibit the formation of new pigments.

Synergistic Action with Vitamin C

Vitamin C reactivates oxidized glutathione, while glutathione plays a role in inhibiting melanin synthesis. These two ingredients work synergistically to create a synergy in improving skin tone.

In conclusion: Glutathione inhibits melanin production and induces pathways for lighter melanin types. Through these actions, it can help improve your skin tone to be natural and even.

Glutathione Management: Which Method is Most Effective?

Many people are familiar with glutathione in oral or injectable forms. However, these approaches have several limitations.

Limitations of Oral Glutathione

Glutathione taken orally has a relatively low absorption rate in the gastrointestinal tract. Furthermore, a significant portion is metabolized in the liver after ingestion, meaning the amount that actually reaches the skin can be very small.

For these reasons, the perceived effect on skin tone improvement from oral intake alone may not be significant.

Considerations for Intravenous Injection

When administered intravenously, glutathione spreads throughout the entire body. Therefore, it is difficult to concentrate the dosage on a specific area.

While this method can be useful for supporting liver function or general systemic antioxidant benefits, it can be considered a less focused approach when targeting facial pigmentation or skin tone improvement.

A New Approach to Glutathione Management

Utilizing Iontophoresis: This method uses a special current to effectively deliver glutathione through the skin barrier to the dermis layer. This can overcome the limitations of oral intake or injection methods.

Targeted Delivery to Desired Areas: Instead of spreading glutathione throughout the body, it can be concentrated and absorbed into facial areas that require improvement for pigmentation or overall skin tone.

Use of Undiluted Solution: To maximize the effects of glutathione, we use undiluted, highly concentrated ampoules. This allows us to fully utilize glutathione's antioxidant and brightening potential.

Glutathione management has been designed to provide a more direct and targeted delivery method compared to oral intake or intravenous injection.

The Necessity of Iontophoresis Absorption Method

Limitations of Oral Intake: When taken orally, glutathione's absorption rate in the gastrointestinal tract is inconsistent, and it undergoes metabolism in the liver, making it difficult to deliver a sufficient amount to the skin.

Limitations of Topical Application: The outermost stratum corneum of the skin acts as a strong barrier, protecting it from external substances. This makes it difficult for water-soluble ingredients like glutathione to penetrate deep into the skin.

Benefits Expected from Iontophoresis Application :

Utilizing Electrical Repulsion: This principle involves using electricity to push negatively charged glutathione, allowing it to effectively pass through the skin's protective barrier.

Electro-Osmosis: This uses electric current to induce the micro-movement of fluids within the skin. This helps expand pathways through which active ingredients can be absorbed.

Delivery to Deep Skin Layers: Instead of remaining only in the epidermis, active ingredients can be transported close to the dermis layer, allowing for deeper and more effective treatment.

In conclusion, iontophoresis is a suitable method for delivering ingredients more directly than oral intake, and deeper into the skin than simple topical application.

Treatment Cycle and Recommended Sessions

Recommended Cycle: Once a week

Optimal Sessions: We generally recommend consistent treatment for 5 sessions or more.

Long-term Maintenance: Regular supplementary treatments can have a positive effect on maintaining a stable skin tone after the initial treatment.